It looks like the ideal drug for weight loss is just around the corner. Contrave has received approval from the FDA for use in the USA in the near future. Contrave is a combination of the anti depressant, bupropion and the anti addiction drug, naltrexone.
Unlike all previous drugs, contrave has no affect on the belly, waist or hips. It works where it matters- in the brain. It has been shown in experimental studies that the drug suppresses the appetite center and helps burn of excess energy.
Bupropion has been around for many years and it is well known that people who use this drug often complain of initial weight loss. However, with bupropion, this initial weight loss is only transient and is soon regained. This is where the addition of naltrexone may help. It is now believed that naltrexone continues to suppress the appetite center and food intake is reduced. While all this sounds great in medical journals and in rats, does the darn combination work in humans?
The drug has been extensively tested in obese people. A large study in obese people compared contrave to exercise and diet counseling. At the end of 1 year, only 60 percent of people remained in the study. Those people who only undertook exercise and diet control lost anywhere from 6-16 pounds in weight over 12 months. In comparison, people who took contrave did excellent. The average weight loss was more than 15% of the body weight, which averaged close to 20-25 pounds in 12 months.
The side effects of contrave included headaches, constipation and nausea. These side effects were common early and easily managed with time. Very few of the patients on contrave suffered emotional side effects like depression or anxiety. In fact most reported feeling good about themselves.
Definitely, this drug works and there was no mucking around with different diet plans because the people just did not feel hungry.
Now the FDA is re-looking at all the side effects, especially on the heart, to make sure that the drug manufacturer is not hiding any negative data. If all things are clear, contrave should be in your corner pharmacy on Jan 31, 2011.
The recommended dose of contrave is two 8 mg naltrexone/90 mg bupropion tablets taken twice a day. When first starting, the dose will be one tablet per week and gradually increased. The only negative about contrave- the pill is not going to come cheap and you have to take it for a whole year. So save up on your vacation to Disney this year and next year when you are slim, trim and gorgeous- you can go to the Bahamas and flaunt the body you have always wanted.
